1. Severe generalized edema is called :
a Myxedema
b pitting edema
C Anasarca
d dependent edema

Explanation -ana- Means throughout everywhere, sarka -means Flesh,
anasarka means swelling of the whole body.
Ans = c Anasarca
2. Which of the following is not a plasma-derived chemical mediators?
a – Cytokines
b Complement components
C kinins
d Coagulation proteins

Explanation –complement components, kinins, and Coagulation proteins are plasma-derived chemical mediators
these factors are already present in plasma in inactive form and get activated when tissue injury or infection occurs.
Cytokines are not plasma-derived chemical mediators. It is cell-derived mediators produced mainly by activated immune cells such as macrophages , Lymphocytes and endothelial cells,
ANS-a-Cytokines
3- Cytokines are secreted by
3. C ytokines are secreted by :
a Neutrophils
b – Lymphocytes
C-Endothelial cells
d All of the above
Explanation –
Neutrophils- It is a type of white blood cell.
Lymphocytes-It is also type of white blood cell
Endothelial cells-Lining cells of blood vessels.
All these cells can secrete cytokines so the correct answer is All of the above.
ANS-d- All of the above
4. Which of the following increases vascular permeability during acute inflammation?
a histamine
b cytokines
c AFP
d both A and B
Explanation –
Histamine and cytokines are both responsible for increase vascular permeability during acute inflammation.
ANS-d -both A and B
5-Mechanism behind the characteristic feature of acute inflammation is :
a- redness and pain
b pancytopenia
C vasodilatation and increased vascular permeability
d spongy bone marrow
- EXPLANATION -Acute inflammation occurs when the body reacts to injury or infection. And this time two things occur 1- -Vasodilatation,2-Increase vascular permeability.
- 1-Vasodilatation -More blood flows to the injured site and causes redness.
- 2-Increased vascular permeability -Fluids and proteins leak out from blood vessels into the tissue which causes swelling.
Ans – c-Vasodilatation and increased vascular permeability.
6. The classical substances that increase the sensitivity of pain receptors by enhancing the pain-provoking effect of bradykinin is
a Nociceptor
b Endorphins
c prostaglandins
d Encephalin
Explanation -Prostaglandin doesn’t directly cause pain; it stimulates the pain nerve.
Ans (c) prostaglandin
7. Which of the following is a substance that decreases pain transmission and causes an inflammatory response?
a Substance p
b Endorphin
C prostaglandin
d histamine
EXPLANATION –
A Substance p- Increases pain
b Endorphin blocks pain signal
C prostaglandin – Increases pain and inflammation
d histamine- Causes swelling, Redness, and itching
Ans (b) Endorphin
- 8. All of the following are evidence of an infection except
a -Elevated WBC
b -purulent drainage
c- primary intention
d -increase leukocytes
Elevated WBC- Sign of infection
purulent drainage – sign of infection
Primary intention – Primary intention means wound healing, no pus
increase leukocytes- sign of infection
Ans (c) primary intention
9. Hemorrhage with the collection of blood in the soft tissue is called
a Contusion
b Purpura
C Ecchymoses
d Hematoma
Ans (d) hematoma
10. Thick Yellow drainage from the wound is known as:
a Sanguineous
b serous – Sanguineous
C serous
d purulent
Explanation -Thick yellow drainage from the wound is purulent.
Ans (d) purulent
Category: MCQ about Medical surgical nursing for AIIMS ,RRB ,
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